Targeting Trends Newsletter 09q3

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page.

Newsletter Highlights

  • SBIR Grant Funded (page 2)
  • New Antibodies (page 2)
  • Anti-Melanopsin Protocol (page 5)
  • Teaser Winners (page 5)
  • Antibody Special Offer (page 7)
  • Complete and Submit the Targeting Teaser online!

Depletion of Microglia by Mac-1-SAP in Mouse Hippocampal Slice Cultures Enhances Ischemia-Like Neurodegeneration – read article

Contributed by Maria Montero (a), Berta Gonzalez (b), Jens Zimmer (a) (a) Anatomy and Neurobiology, University of Southern Denmark, Denmark (b) Histology Unit, Autonomous University of Barcelona, SpainProduct information related to cover article: Mac-1-SAP (Cat. #IT-06 mouse/human)

SBIR Grant Funded: Selective Activation in Neuronal Populations – read article

New Antibodies (see complete list of antibodies)

Recent Scientific References – read online

  • Abbott SB, Stornetta RL, Fortuna MG, Depuy SD, West GH, Harris TE, Guyenet PG (2009) Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci 29:5806-5819. (Cat. #IT-03)
  • Antonini V, Prezzavento O, Coradazzi M, Marrazzo A, Ronsisvalle S, Arena E, Leanza G (2009) Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J Neurochem 109:744-754. (Cat. #IT-01)
  • Botly LC, De Rosa E (2009) Cholinergic deafferentation of the neocortex using 192 IgG-saporin impairs feature binding in rats. J Neurosci 29:4120-4130. (Cat. #IT-01)
  • Browning PG, Gaffan D, Croxson PL, Baxter MG (2009) Severe Scene Learning Impairment, but Intact Recognition Memory, after Cholinergic Depletion of Inferotemporal Cortex Followed by Fornix Transection. Cereb Cortex [Epub]. (Cat. #IT-15)
  • Halasz J, Zelena D, Toth M, Tulogdi A, Mikics E, Haller J (2009) Substance P neurotransmission and violent aggression: the role of tachykinin NK(1) receptors in the hypothalamic attack area. Eur J Pharmacol 611:35-43. (Cat. #IT-07)
  • Lawhorn C, Smith DM, Brown LL (2009) Partial ablation of mu-opioid receptor rich striosomes produces deficits on a motor-skill learning task. Neuroscience [Epub]. (Cat. #IT-12; Cat. #PR-01)
  • Lujan HL, Palani G, Chen Y, Peduzzi JD, Dicarlo SE (2009) Targeted ablation of cardiac sympathetic neurons reduces resting, reflex and exercise-induced sympathetic activation in conscious rats. Am J Physiol Heart Circ Physiol 296:H1305-1311. (Cat. #IT-14)
  • Montero Dominguez M, Gonzalez B, Zimmer J (2009) Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia. Exp Neurol 218:11-23. (Cat. #IT-06)
  • Nattie E, Li A (2009) Central chemoreception is a complex system function that involves multiple brain stem sites. J Appl Physiol 106:1464-1466. (Cat. #IT-23; Cat. #IT-03)
  • Paban V, Chambon C, Manrique C, Touzet C, Alescio-Lautier B (2009) Neurotrophic signaling molecules associated with cholinergic damage in young and aged rats Environmental enrichment as potential therapeutic agent. Neurobiol Aging [Epub]. (Cat. #IT-01)
  • Radley JJ, Gosselink KL, Sawchenko PE (2009) A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response. J Neurosci 29:7330-7340. (Cat. #IT-32; Cat. #IT-35)
  • Ramanathan D, Tuszynski MH, Conner JM (2009) The basal forebrain cholinergic system is required specifically for behaviorally mediated cortical map plasticity. J Neurosci 29:5992-6000. (Cat. #IT-01)
  • Ray AP, Chebolu S, Ramirez J, Darmani NA (2009) Ablation of least shrew central neurokinin NK1 receptors reduces GR73632-induced vomiting. Behav Neurosci 123:701-706. (Cat. #IT-11; Cat. #IT-21; Cat. #PR-01)
  • Wiley RG, Lemons LL, Kline RHt (2009) Neuropeptide Y receptor-expressing dorsal horn neurons: role in nocifensive reflex responses to heat and formalin. Neuroscience 161:139-147. (Cat. #IT-28; Cat. #IT-21)
  • Zhang W, Gardell S, Zhang D, Xie JY, Agnes RS, Badghisi H, Hruby VJ, Rance N, Ossipov MH, Vanderah TW, Porreca F, Lai J (2009) Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors. Brain 132:778-787. (Cat. #IT-12; Cat. #IT-31; Cat. #PR-01)

Targeting Talk (see text)

Upcoming Events

  • La Jolla Drug Development Day • La Jolla, CA — July 22, 2009
  • Society for Neuroscience, Booth #619 • Chicago, IL — October 17-21, 2009

Featured Services

Targeting Tools: Featured Products

  • Try our Best-Selling Antibodies (see antibody catalog)
  • Buy One Get One Free! (through September 30, 2009)

Gangsta Gallery

Targeting Technology Tutorial