Anti-CD44-SAP [IT-72]

a tool for eliminating cells that express all isoforms of the CD44 receptor in multiple species; targeted via the rat monoclonal antibody to mouse CD44 (clone IM7), eliminated via saporin

SKU: IT-72 Category: Product Size: 25 ug, 100 ug, 250 ug, 1 mg | Antibody Type: Monoclonal | Host: Rat | Reactivity: baboon, Bovine, Cat, dog, ferret, horse, Human, monkey, Mouse, pig | Conjugate: streptavidin-saporin | Usage: eliminates cells |

CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such a lymphocyte activation, recirculation and homing, hematopoieses, and tumor metastasis. CD44 has been considered an activity marker and potential novel therapeutic target in multiple sclerosis and is associated with relapses in non-small cell lung cancers.

Anti-CD44-SAP eliminates cells expressing all isoforms of CD44.

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