Goat IgG-SAP is the perfect control for use with secondary conjugates. The secondary antibody conjugates are used with a bivalent primary antibody (a mouse monoclonal, rabbit polyclonal, human monoclonal, rat monoclonal, or IgM mouse monoclonal) to determine if the primary antibody can internalize saporin and would, therefore, be suitable for conjugation as a primary immunotoxin. Goat IgG-SAP, used in place of the secondary antibody conjugate, will give a definitive baseline for comparison of the activity of the primary antibody to internalize.
Goat IgG-SAP serves as a control for goat IgG-containing immunolesioning agents.
keywords: saporin, control, IgG