The orexin 1 and orexin 2 receptors are found in the perifornical area/latero-posterior hypothalamus, and projections from this area cover much of the brain. These receptors have been implicated in various neurophysiological and neuropsychological disorders such as narcolepsy, insomnia, drug addiction, anxiety, and migraine headaches.
Anti-OX1r-SAP eliminates mouse, rat, and guinea pig cells expressing the orexin 1 receptor. All other cells are left untouched.
The following control is included for validating the specificity of the beta conjugate: Rabbit IgG-SAP (Cat. #IT-35).
This product is being offered as part of our Beta Testing program. It has saporin activity confirmed, peptide sequences published/confirmed, and/or antibody binding specificity published/confirmed. It has not been characterized or reported in scientific literature. The researcher who first publishes data* will receive a $500 credit for use on ATS products.
*Data subject to review by the scientific team at ATS. See complete details here.