Cholera Toxin (CT) is produced by a Gram negative bacteria, Vibrio cholera, and is a member of the AB toxin family. The holotoxin consists of a single A subunit (CTA) that has a molecular weight of 27 kDA and five surrounding B subunits (CTB). After the cell internalizes CT, CTA activates the cAMP pathway by ribosylating adenylate cyclase. The effect of CTA on adenylate cyclase provides a useful tool for studying signal transduction mechanisms. This antibody is used to bind to CTA.
This antibody recognizes the catalytic A subunit of cholera toxin (CTA). Recombinant CTA was used as the immunogen. It is routinely tested by ELISA.
Applications include ELISA and immunoblotting.
keywords: cholera toxin subunit A, CT, CTA, CTB, catalytic A subunit, Anti-CTA, Anti-Cholera Toxin subunit A