Cholera Toxin subunit A Rabbit Polyclonal [AB-43]


SKU: AB-43 Category: Quantity: 100 ul | Antibody Type: Polyclonal | Host: Rabbit | Conjugate: unconjugated | Usage: ELISA, immunoblotting |

Cholera Toxin (CT) is produced by a Gram negative bacteria, Vibrio cholera, and is a member of the AB toxin family. The holotoxin consists of a single A subunit (CTA) that has a molecular weight of 27 kDA and five surrounding B subunits (CTB). After the cell internalizes CT, CTA activates the cAMP pathway by ribosylating adenylate cyclase. The effect of CTA on adenylate cyclase provides a useful tool for studying signal transduction mechanisms. This antibody is used to bind to CTA.

This antibody recognizes the catalytic A subunit of cholera toxin (CTA). Recombinant CTA was used as the immunogen. It is routinely tested by ELISA.

Applications include ELISA and immunoblotting.

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