Growth hormone-releasing factor (GRF) is a 44-amino-acid amidated peptide that stimulates the pituitary to release the 197-amino-acid protein growth hormone (GH or somatotropin). GRF is associated with neuronal cell bodies in the arcuate nucleus of the hypothalamus. GH acts as a general anabolic stimulant, increases release of insulin-like growth factor-I (IGF-I), cell growth and bone sulfation.
This antibody recognizes the growth hormone releasing hormone/factor in rat. Synthetic hpGRF 1-40 was used as immunogen. The antibody was purified from polyclonal antiserum using a CRF affinity column. It has been conjugated to the fluorescent dye Alexa488. The antibody is routinely tested by immunoblotting.
Applications include immunoblotting and ELISA.