antibodies

Wang F, Jing P, Zhan P, Zhang H (2020) Thyroid hormone in the pathogenesis of congenital intestinal dysganglionosis. Pediatr Dev Pathol 23(4):285-295. doi: 10.1177/1093526620908984 PMID: 32212960

Objective: To investigate the role of thyroid hormone (TH) in the pathogenesis of intestinal dysganglionosis (ID).

Summary: 6-propyl-2-thiouracil (PTU) inhibited TH production, reduced the number of enteric neurons, impaired intestinal motility, and impeded ENCC mitosis in zebrafish, suggesting a possible role of CH in the pathogenesis of ID.

Usage: Immunostaining (1:60); AB-N01AP: NGFr (mu p75) Rabbit Polyclonal

Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

Qin J, Wang M, Zhao T, Xiao X, Li X, Yang J, Yi L, Goffinet AM, Qu Y, Zhou L (2020) Early forebrain neurons and scaffold fibers in human embryos. Cerebral Cortex 30(3):913–928. doi: 10.1093/cercor/bhz136 PMID: 31298263

Objective: To study neural progenitor proliferation, neuronal migration, areal organization, and pioneer axon wiring are critical events during early forebrain development.

Summary: Axons from pioneer neurons in prethalamus, ventral telencephalon, and cortical preplate cross the diencephalon–telencephalon junction and the pallial–subpallial boundary, forming scaffolds that could guide thalamic and cortical axons at later stages.

Usage: Immunofluorescence (1:600); AB-N01AP: NGFr (mu p75) Rabbit Polyclonal, affinity-purified

Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

Li X, Yu M, Yang C (2020) YY1-mediated overexpression of long noncoding RNA MCM3AP-AS1 accelerates angiogenesis and progression in lung cancer by targeting miR-340-5p/KPNA4 axis. J Cell Biochem 121(3):2258-2267. doi: 10.1002/jcb.29448 PMID: 31693222

Usage: western (1:1000)

Related Products: Fibroblast Growth Factor Rabbit Polyclonal, mammalian (Cat. #AB-07)

Serre NBC, Sarthou M, Gigarel O, Figuet S, Corso M, Choulet J, Rofidal V, Alban C, Santoni V, Bourguignon J, Verbruggen N, Ravanel S (2020) Protein lysine methylation contributes to modulating the response of sensitive and tolerant Arabidopsis species to cadmium stress. Plant Cell Environ 43(3):760-774. doi: 10.1111/pce.13692 PMID: 31759334

Usage: Western blot

Related Products: Tri-methyl Lysine Rabbit Polyclonal (Cat. #AB-265)

Wu X, Cao Z, Chen H, Ou Q, Huang X, Wang Y (2020) Downregulation of Linc-RNA activator of myogenesis lncRNA participates in FGF2-mediated proliferation of human periodontal ligament stem cells. J Periodontol 91(3):422-427. doi: 10.1002/JPER.19-0317 PMID: 31378921

Usage: Western (1:1200)

Related Products: Fibroblast Growth Factor Rabbit Polyclonal, mammalian (Cat. #AB-07)

Li S, Zhao W, Tao Y, Liu C (2020) Fugan Wan alleviates hepatic fibrosis by inhibiting ACE/Ang II/AT-1R signaling pathway and enhancing ACE2/Ang 1-7/Mas signaling pathway in hepatic fibrosis rat models. Am J Transl Res 12(2):592-601. PMID: 32194907

Objective: To investigate protective effects of Fugan Wan (FGW) on hepatic fibrosis and clarify associated mechanisms.

Summary: FGW alleviated hepatic fibrosis by inhibiting ACE/Ang II/AT-1R signaling and enhancing ACE2/Ang 1-7/Mas signaling pathway in hepatic fibrosis rat models.

Usage: Western blot

Related Products: Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP)

Seitter H, Sothilingam V, Benkner B, Garrido MG, Kling A, Pirone A, Seeliger M, Münch TA (2020) Voltage-gated calcium channel subunit α2δ-3 shapes light responses of mouse retinal ganglion cells mainly in low and moderate light levels. bioRxiv 2020.02.10.941807. doi: 10.1101/2020.02.10.941807

Related Products: Melanopsin Rabbit Polyclonal, affinity-purified (Cat. #AB-N39)

Cui LJ, Chen WH, Liu AL, Han X, Jiang SX, Yuan F, Zhong YM, Yang XL, Weng SJ (2020) nGnG amacrine cells and Brn3b-negative M1 ipRGCs are specifically labeled in the ChAT-ChR2-EYFP mouse. Invest Ophthalmol Vis Sci 61(2):14. doi: 10.1167/iovs.61.2.14 PMID: 32049344

Summary: The authors speculated that type II cells might be ipRGCs. This was later verified by the strong immunostaining of type II cells in response to the melanopsin antibody UF006 (100%, 141 of 141 cells collected from 5 retinas, Figs. 6B1–B3), which probes multiple ipRGC subtypes.

Usage: Immunostaining 1:10000

Related Products: Melanopsin Rabbit Polyclonal (Cat. #AB-N38)

Ali A, Syed SM, Jamaluddin MFB, Colino-Sanguino Y, Gallego-Ortega D, Tanwar PS (2020) Cell lineage tracing identifies hormone-regulated and wnt-responsive vaginal epithelial stem cells. Cell Rep 30(5):1463-1477.e7. doi: 10.1016/j.celrep.2020.01.003 PMID: 32023462

Objective: To learn more about the role of Wnt signaling in vaginal epithelium (VE) homeostasis.

Summary: Data define heterogeneity in VE and identify VE stem cells. It was shown that canonical Wnt/b-catenin signaling is required for the proliferation and differentiation of VE stem cells.

Usage: histology and immunostaining (1:250)

Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)

Landrigan J, Dwyer Z, Beauchamp S, Rodriguez R, Fortin T, Hayley S (2020) Quantum dot conjugated saporin activates microglia and induces selective substantia nigra degeneration. NeuroToxicology 76:153-161. doi: 10.1016/j.neuro.2019.11.007 PMID: 31738977

Objective: To assess the impact of Quantum Dots (QDs) alone and QDs conjugated to Saporin, on substantia nigra microglia and dopamine neurons.

Summary: QDs might be a viable route for toxicant delivery and also have an added advantage of being fluorescently visible. Ultimately, we found SNc neurons to be exceptionally vulnerable to QD-saporin and suggest that this could be a novel targeted approach to model Parkinson’s Disease-like inflammatory pathology.

Usage: Biotin-labeled saporin chicken polyclonal was mixed with QDs coated with streptavidin. 2  μl of QDs (1 μM) were mixed with 2  μL of biotinylated saporin (56 μM) and 76  μL of phosphate buffer solution was added.

Related Products: Saporin Chicken Polyclonal, affinity-purified biotin-labeled (Cat. #AB-17APBT)