Marcos B, Gil-Bea FJ, Hirst WD, Garcia-Alloza M, Ramirez MJ (2006) Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine release. Eur J Neurosci 24(5):1299-1306. doi: 10.1111/j.1460-9568.2006.05003.x
Summary: The authors investigated a potential link between 5-HT6 receptors, cholinergic activity, and learning. After 0.067 µg of 192-Saporin (Cat. #IT-01) was injected into each hemisphere of the nucleus basalis magnocellularis in the basal forebrain of rats, 5-HT6 receptor mRNA and protein expression were measured. Results demonstrate the involvement of multiple neurotransmitter systems in neurochemical actions following 5-HT6 receptor blockade.
Related Products: 192-IgG-SAP (Cat. #IT-01)