Saenz C, Dominguez R, de Lacalle S (2006) Estrogen contributes to structural recovery after a lesion. Neurosci Lett 392(3):198-201. doi: 10.1016/j.neulet.2005.09.023
Summary: The authors evaluated the trophic effects of 17ß-estradiol (E2) on cholinergic neurons of the basal forebrain after lesioning with 192-IgG-SAP (Cat. #IT-01). Ovariectomized female rats received 200 nl of 0.075 mg/ml 192-IgG-SAP followed by a subcutaneous pellet of E2, which was released over 60 days. Dendritic size in ovariectomized rats receiving the E2 was the same as in control animals, while ovariectomized rats receiving a placebo displayed a significant reduction in dendritic arborization.
Related Products: 192-IgG-SAP (Cat. #IT-01)