Ross RS, McGaughy J, Eichenbaum H (2005) Acetylcholine in the orbitofrontal cortex is necessary for the acquisition of a socially transmitted food preference. Learn Mem 12(3):302-306. doi: 10.1101/lm.91605
Summary: Cortical involvement in social transmission of food preference (STFP) has not been established, but the importance of the orbitofrontal cortex (OFC) in odor-guided learning is known. The OFC of rats was injected twice with 192-Saporin (Cat. #IT-01), then the rats were trained in STFP. Depletion of cholinergic neurons in the OFC impaired expression of the odor association, indicating that cholinergic function in the OFC is essential for this form of associative learning.
Related Products: 192-IgG-SAP (Cat. #IT-01)