Hartonian I, de Lacalle S (2005) Compensatory changes in cortical cholinergic innervation in the rat following an immunotoxic lesion. Restor Neurol Neurosci 23(2):87-96.
Summary: The ability of damaged axons to grow and functionally reinnervate damaged areas of the brain is well documented. Here the authors study this process in the context of rats lesioned with 192-Saporin (Cat. #IT-01). 10.5 ng of the immunotoxin was injected into the right horizontal diagonal band of Broca, and animals were examined from 2 to 24 weeks later. Although the functionality of the neuronal ingrowth was not examined, surviving neurons did extend their terminals into the denervated area.
Related Products: 192-IgG-SAP (Cat. #IT-01)