Harrell LE, Parsons DS, Kolasa K (2005) The effect of central cholinergic and noradrenergic denervation on hippocampal sympathetic ingrowth and apoptosis-like reactivity in the rat. Brain Res 1033(1):68-77. doi: 10.1016/j.brainres.2004.11.021
Summary: Cholinergic denervation of the hippocampus is followed by ingrowth of peripheral sympathetic fibers originating from the superior cervical ganglion. The authors injected 1 µg of 192-Saporin (Cat. #IT-01) into the medial septum of rats along with a noradrenergic fiber neurotoxin to investigate whether the noradrenergic system was involved with this ingrowth as well. The data provide more evidence that hippocampal sympathetic ingrowth can be stimulated by cholinergic denervation alone.
Related Products: 192-IgG-SAP (Cat. #IT-01)