Estacio MA, Tsukamura H, Reyes BA, Uenoyama Y, I’anson H, Maeda K (2004) Involvement of brainstem catecholaminergic inputs to the hypothalamic paraventricular nucleus in estrogen receptor alpha expression in this nucleus during different stress conditions in female rats. Endocrinology 145(11):4917-4926. doi: 10.1210/en.2004-0469
Summary: Norepinephrine release in the paraventricular nucleus (PVN) is increased during periods of metabolic stress. The authors hypothesized that noradrenergic inputs to the PVN may also mediate estrogen receptor a (ERa) expression in the PVN during metabolic stress. 20 ng of Anti-DBH-SAP (Cat. #IT-03) was injected bilaterally into the PVN of rats, and ERa expression was examined in several stress models. Results indicate that during metabolic stress catecholaminergic inputs to the PVN play a major role in mediating the induction of ERa expression.
Related Products: Anti-DBH-SAP (Cat. #IT-03)