Cadiacio CL, Milner TA, Gallagher M, Pierce JP (2003) Hilar neuropeptide Y interneuron loss in the aged rat hippocampal formation. Exp Neurol 183(1):147-158. doi: 10.1016/s0014-4886(03)00126-2
Summary: The authors investigate the loss of neuropeptide Y-immunoreactive (NPY-I) interneurons in the dentate gyrus of aged rats. Their results show a loss of a select group of interneurons in these animals. The behavioral as well as structural changes correlated with the results of previous studies on young rats treated with 192-Saporin (Cat. #IT-01). NPY-I neurons may therefore be affected by age-related losses of cholinergic neurons in the basal forebrain.
Related Products: 192-IgG-SAP (Cat. #IT-01)