Lehmann O, Grottick AJ, Cassel JC, Higgins GA (2003) A double dissociation between serial reaction time and radial maze performance in rats subjected to 192 IgG-saporin lesions of the nucleus basalis and/or the septal region. Eur J Neurosci 18(3):651-666. doi: 10.1046/j.1460-9568.2003.02745.x
Summary: Using 0.4-µl injections containing 0.4 µg of 192-Saporin (Cat. #IT-01) into either the nucleus basalis magnocellularis, the medial septum/vertical limb of the diagonal band of Broca, or both, the authors examined the contributions of the p75 receptor-positive neurons on cognitive function in rats. Data indicate there is a functional dissociation between the two pathways in attention and memory.
Related Products: 192-IgG-SAP (Cat. #IT-01)