Lamprea MR, Cardenas FP, Silveira R, Walsh TJ, Morato S (2003) Effects of septal cholinergic lesion on rat exploratory behavior in an open-field. Braz J Med Biol Res 36(2):233-238. doi: 10.1590/s0100-879×2003000200011
Summary: Exploratory behavior triggered by novelty involves the medial septum. The authors lesioned the medial septum in rats with 237.5-ng injections of 192-Saporin (Cat. #IT-01) and examined the behavior of these animals in a model for novelty. The results suggest not only do septohippocampal cholinergic mechanisms contribute to the motivation to explore new environments, they also are related to the acquisition and storage of spatial information.
Related Products: 192-IgG-SAP (Cat. #IT-01)