Stornetta RL, Rosin DL, Wang H, Sevigny CP, Weston MC, Guyenet PG (2003) A group of glutaminergic interneurons expressing high levels of both neurokinin-1 receptors and somatostatin identifies the region of the pre-Bötzinger complex. J Comp Neurol 455(4):499-512. doi: 10.1002/cne.10504
Summary: Study of the pre-Bötzinger complex (pre-BötC) has been hindered by the lack of a specific marker. Using SSP-SAP (Cat. #IT-11, three 0.313-ng unilateral injections in the rostral part of the ventral respiratory group) coupled with in situ hybridization and the labeling of selected markers, the authors examined whether somatostatin (SST) might be a marker for this region. The data suggest that a subgroup of cells containing high levels of SST and neurokinin-1 receptor immunoreactivity may identify the pre-BötC.
Related Products: SSP-SAP (Cat. #IT-11)