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  4. Effect of 192 IgG-saporin on circadian activity rhythms, expression of P75 neurotrophin receptors, calbindin-D28K, and light-induced Fos in the suprachiasmatic nucleus in rats.

Effect of 192 IgG-saporin on circadian activity rhythms, expression of P75 neurotrophin receptors, calbindin-D28K, and light-induced Fos in the suprachiasmatic nucleus in rats.

Beaule C, Amir S (2002) Effect of 192 IgG-saporin on circadian activity rhythms, expression of P75 neurotrophin receptors, calbindin-D28K, and light-induced Fos in the suprachiasmatic nucleus in rats. Exp Neurol 176(2):377-389. doi: 10.1006/exnr.2002.7969

Summary: The authors used bilateral icv injections of 200 ng of 192-Saporin (Cat. #IT-01) to investigate the contribution of p75NTR-expressing neurons to the determination of a circadian rhythm. The data show that p75NTR-expressing neurons are not essential for this process.

Related Products: 192-IgG-SAP (Cat. #IT-01)

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