Ballmaier M, Casamenti F, Scali C, Mazzoncini R, Zoli M, Pepeu G, Spano PF (2002) Rivastigmine antagonizes deficits in prepulse inhibition induced by selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis. Neuroscience 114(1):91-98. doi: 10.1016/s0306-4522(02)00234-8
Summary: The authors injected 300 nl of 400 ng/ml 192-Saporin (Cat. #IT-01) bilaterally into the nucleus basalis magnocellularis of rats, then treated the lesioned animals with rivastigmine, a cholinesterase inhibitor. Animals treated with rivistagmine exhibited raised levels of cortical acetylcholine, in contrast to undetectable acetylcholine levels in lesioned animals not treated with rivastigmine.
Related Products: 192-IgG-SAP (Cat. #IT-01)