McGaughy J, Everitt BJ, Robbins TW, Sarter M (2000) The role of cortical cholinergic afferent projections in cognition: impact of new selective immunotoxins. Behav Brain Res 115:251-263. doi: 10.1016/s0166-4328(00)00262-x PMID: 11000424
Summary: Discusses the advancements of animal models through immunotoxins targeting cholinergic neurons, 192-IgG-SAP (IT-01) and ME20.4-SAP (IT-15), and how their selectivity has allowed Alzheimer’s research advancements. Discusses the benefits of immunotoxin animal model studies over neuropsychological, psychopharmacological and excitotoxic studies.
Related Products: 192-IgG-SAP (Cat. #IT-01), ME20.4-SAP (Cat. #IT-15)