Fu E, Li Z (2024) Extracellular vesicles: A new frontier in the theranostics of cardiovascular diseases. iRadiology 2(3):240-259. doi: 10.1002/ird3.77
Objective: To delve into the evolving landscape of extracellular vesicles (EVs), uncovering their diagnostic and therapeutic prospects and emphasizing their growing importance in shaping the future of cardiovascular theranostics
Summary: The ability of EVs to act as conduits of molecular information, orchestrate cellular responses, and influence the behaviors of recipient cells will allow precision interventions in cardiovascular disease (CVD) treatment. The continuous refinement of biomaterial‐based strategies and innovative delivery methods will improve the precision and efficacy of EV interventions, establishing a solid foundation for their experimental application. Enhanced cellular uptake and cytosolic release of exosomes has been achieved by combining a pH‐sensitive fusogenic peptide and cationic lipids. This method facilitates the efficient delivery of encapsulated molecules, including 70kD adextran and the ribosome‐inactivating protein named saporin.
Related Products: Saporin (Cat. #PR-01)
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