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Rational engineering of cytosolic delivery systems for protein therapeutics

Lv J, Liu X, Yin L, Cheng Y (2024) Rational engineering of cytosolic delivery systems for protein therapeutics. Acc Mater Res doi: 10.1021/accountsmr.4c00149

Objective: To summarize recent advances in the rational design of cytosolic protein delivery systems.

Summary: Saporin, a cell membrane-impermeable toxin, kills cancer cells by inhibiting protein synthesis. To fully utilize the therapeutic potential of saporin, the authors developed a series of polymeric carriers to deliver saporin into tumor cells.

Usage: Polymeric carriers were used to deliver saporin into tumor cells

Related Products: Saporin (Cat. #PR-01)

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