Berger-Sweeney J, Stearns NA, Frick KM, Beard B, Baxter MG (2000) Cholinergic basal forebrain is critical for social transmission of food preferences. Hippocampus 10(6):729-738. doi: 10.1002/1098-1063(2000)10:6<729::AID-HIPO1010>3.0.CO;2-M PMID: 11153718
Objective: To examine whether the cholinergic basal forebrain plays a role in non-spatial associative memory, specifically, the social transmission of food preferences.
Summary: The authors lesioned rats with 192-IgG-SAP to create selective lesions of basal forebrain cholinergic neurons and examine the rats ability to recall learned social food preference. It was shown that this type of memory was strongly associated with cholinergic activity and implicates the cholinergic projection to the neocortex in the formation of social memories.
Usage: Rats were subjected to 192 IgG-SAP (IT-01) injections at 0.175 mg/ml spread across the medial septum and vertical limb of the diagonal band of Broca bilaterally for a total of 2 microliters.
Related Products: 192-IgG-SAP (Cat. #IT-01)