Zeynalzadeh E, Khodadadi E, Khodadadi E, Ahmadian Z, Kazeminava F, Rasoulzadehzali M, Samadi Kafil H (2024) Navigating the neurological frontier: Macromolecular marvels in overcoming blood-brain barrier challenges for advanced drug delivery. Heliyon 10(15):e35562. doi: 10.1016/j.heliyon.2024.e35562 PMID: 39170552
Objective: To understand how nanoparticles interact with the blood-brain barrier.
Summary: Enhancing the bioavailability of nano formulations at the intended site is critical. The use of surface ligands that target brain endothelial cell receptors may improve BBB penetration. In summary, nanomaterials offer vast potential in the realm of brain-targeted therapies, from early detection to effective treatment.
Usage: Saporin (PR-01) was cited for protein toxin delivery as a therepeutic agent for BBB penetration.
Related Products: Saporin (Cat. #PR-01)
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