Xia L, Luo L, Liu J, Liu L, Han H, Xia R, Guo L, Xie J, Tang L (2024) A glycoprotein-based surface-enhanced raman spectroscopy–lateral flow assay method for abrin and ricin detection. Toxins (Basel) 16(7):312. doi: 10.3390/toxins16070312 PMID: 39057952
Objective: To generate stable and high-affinity nanotags, via an efficient freezing method, to serve as the capture module for surface-enhanced Raman spectroscopy (SERS) and lateral flow assay (LFA) (SERS-LFA).
Summary: The detection method demonstrated good inter-batch and intra-batch reproducibility among the test strips, and the detection could be completed within 15 min, indicating the suitability of this SERS-LFA method for the on-site rapid detection of abrin and ricin toxins.
Usage: The specificity of the test strip for abrin was assessed against RCA120, AAG, RTB, RTA, Stx1, Stx2, saporin, and SEB. Proteins, such as RTA, Stx 1, Stx 2,saporin, and SEB, did not cross-react with this assay.
Related Products: Saporin (Cat. #PR-01)