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Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

Singh RR, Mondal I, Janjua T, Popat A, Kulshreshtha R (2023) Engineered smart materials for RNA based molecular therapy to treat Glioblastoma. Bioact Mater 33:396-426. doi: 10.1016/j.bioactmat.2023.11.007 PMID: 38059120

Objective: A review of non-coding RNA therapy and its targeted delivery of nucleic acids to treat Glioblastoma, emphasizing smart nano-materials.

Summary: Nano-carriers of ncRNA can offer unique advantages in fighting, such as low cytotoxicity, ability to cross the blood-brain barrier, stealth to bypass immune detection, prolonged release of the cargo, improved circulatory time, and also targeted therapy.

Usage: Saporin as a payload to the nano-carriers angiopep-2 peptide and RAP12.

Related Products: Saporin (Cat. #PR-01)

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