Hernández-Barranco A, Santos V, Mazariegos MS, Caleiras E, Nogués L, Mourcin F, Léonard S, Oblet C, Genebrier S, Rossille D, Benguría A, Sanz A, Vázquez E, Dopazo A, Efeyan A, Ortega-Molina A, Cogne M, Tarte K, Peinado H (2024) NGFR regulates stromal cell activation in germinal centers. Cell Rep 43(2):113705. doi: 10.1016/j.celrep.2024.113705 PMID: 38307025
Objective: To study the effect of NGFR loss on lymph node organization and function, demonstrating that NGFR depletion leads to spontaneous germinal center (GC) formation and an expansion of the GC B cell compartment.
Summary: Results show that NGFR is involved in maintaining GC structure and function, participating in GC activation, antibody production, and immune tolerance.
Usage: Anti-NGFR Alexa488-labeled used in Flow Cytometry (1:200) (Cat# AB-N01AP-FLA).
Related Products: NGFR (mu p75) Rabbit Polyclonal, affinity-purified Alexa488-labeled (Cat. #AB-N01AP-FLA)