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ALK upregulates POSTN and WNT signaling to drive neuroblastoma

Huang M, Fang W, Farrel A, Li L, Chronopoulos A, Nasholm N, Cheng B, Zheng T, Yoda H, Barata MJ, Porras T, Miller ML, Zhen Q, Ghiglieri L, McHenry L, Wang L, Asgharzadeh S, Park J, Gustafson WC, Matthay KK, Maris JM, Weiss WA (2024) ALK upregulates POSTN and WNT signaling to drive neuroblastoma. Cell Rep 43(3):113927. doi: 10.1016/j.celrep.2024.113927 PMID: 38451815

Objective: To determine how anaplastic lymphoma kinase (ALK) contributes to tumor formation.

Summary: ALK partially drives neuroblastoma through a feedforward loop between POSTN and WNT signaling.

Usage: AB-N07 Anti-NGFR Immunofluorescence (1:250).

Related Products: NGFR (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07)

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