Antonia-Nancy H, Matsumoto M, Tahara Y (2023) Self-assembled nanogels consisting of cholesterol-bearing polysaccharides and their applications in medicine. (eds. Dr. Chukwuebuka Emmanuel Umeyor, Dr. Emmanuel Uronnachi and Dr. Pratik Kakade). In: Hydrogels and Nanogels – Applications in Medicine doi: 10.5772/intechopen.1001981
Objective: Using iron oxide-containing nano-gels containing saporin to magnetically guide the targeting of saporin.
Summary: Nanogels containing inorganics are an emerging tool to direct the targeting of drugs within the body. Saporin was bound in a cholesterol-bearing pullulan nanogel with particles of iron oxide was magnetically steered through the chaperoning gel to treat a model of oral cancer.
Usage: Using Saporin bound to magnetic nanogel to target a model of oral cancer. See Also: Saporin usage form these two papers: KawasakiR, SasakiY, KatagiriK, MukaiS-A, SawadaS-I, AkiyoshiK. Magnetically guided protein transduction by hybrid Nanogel chaperones with iron oxide nanoparticles. Angewandte Chemie, International Edition. 2016;55:11377-11381.DOI:10.1002/anie.201602577 KawasakiR, SasakiY, NishimuraT, KatagiriK, MoritaK-I, SekineY, etal. Magnetically navigated protein transduction In vivo using iron oxide-Nanogel chaperone hybrid. Advanced Healthcare Materials. 2021;10:2001988.DOI:10.1002/adhm.202001988
Related Products: Saporin (Cat. #PR-01)