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Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract

Zlatkovic J, Dalmau Gasull A, Hägg D, Font-Gironès F, Bellman J, Meister B, Palsdottir V, Ruud J, Ohlsson C, Dickson SL, Anesten F, Jansson JO (2023) Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract. J Neuroendocrinol 35(12):e13352. doi: 10.1111/jne.13352 PMID: 37885347

Objective: To show that the feed-back regulation of body weight, initiated by a novel leptin-independent body weight homeostat, involves a CNS mechanism

Summary: In conclusion, increased load appears to reduce body weight and food intake via activation of norepinephrine neurones in the medial nucleus of the solitary tract.

Usage: 5 ng of Anti-DBH-SAP (IT-03) was bilaterally injected into the NTS in Male C57/B6J mice and Sprague–Dawley rats.

Related Products: Anti-DBH-SAP (Cat. #IT-03)

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