Miles AJ, Drew ED, Wallace BA (2023) DichroIDP: a method for analyses of intrinsically disordered proteins using circular dichroism spectroscopy. Commun Biol 6(1):823. doi: 10.1038/s42003-023-05178-2 PMID: 37553525
Objective: To use DichroIDP software to analyze secondary structures of proteins containing disordered structures via circular dichroism spectroscopy.
Summary: Globular proteins have specific shapes and mainly contain standard secondary structures. In contrast, intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) have flexible chains with limited persistent secondary structures.
Usage: Saporin is used to study secondary and tertiary protein structure
Related Products: Saporin (Cat. #PR-01)