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A novel anxiety process biomarker via electrovestibulography

Bosecke C (2022) A novel anxiety process biomarker via electrovestibulography. University of Manitoba Thesis.

Objective: Use electrophysiological technique of Electrovestibulography to measure field potentials caused by vestibular neurons in the ear canal in order to identify biomarkers associated with anxiety disorder.

Summary: Anxiety disorders have no known biomarkers and are diagnosed based on symptoms. Identifying biomarkers could help improve the accuracy of anxiety disorder diagnosis, but can be difficult because the brain regions implicated in anxiety are very deep within the brain.

Usage: 192 IgG-SAP (Cat. #IT-01) was used to lesion the cholinergic medial septum inputs to the hippocampus. 192 IgG-saporin was diluted to 0.35 µg/µl with sterile saline, and 0.4 µl was infused bilaterally into each ventral site of the medial septum.

Related Products: 192-IgG-SAP (Cat. #IT-01)

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