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Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats

Andrews JL, Newell KA, Matosin N, Huang XF, Fernandez F (2018) Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats. Neuronal Signal 2(3):NS20180059. doi: 10.1042/NS20180059 PMID: 32714588

Objective: To investigate the effects of perinatal phencyclidine (PCP) administration on levels of expression of Lingo-1 signaling proteins in the prefrontal cortex, a critical region for cognitive processing that is consistently reported to be disrupted in schizophrenia.

Summary: Study showed alterations in Lingo-1 signaling pathway proteins in the prefrontal cortex of rats from a neurodevelopmental PCP model of schizophrenia.

Usage: protein expression

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