Boakye PA, Rancic V, Whitlock KH, Simmons D, Longo FM, Ballanyi K, Smith PA (2019) Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1. J Neurophysiol 121(6):2308-2322. doi: 10.1152/jn.00839.2018 PMID: 30995156
Objective: To find missing steps in understanding how peripheral injury instigates central sensitization and the onset of neuropathic pain.
Summary: Colony-stimulating factor 1 (CSF-1) increases excitatory drive to excitatory neurons via a BDNF-dependent mechanism and decreases excitatory drive to inhibitory neurons via BDNF-independent processes.
Usage: immunohistochemistry (1:500)
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