Wu W, Wu XL, Ji YQ, Gao Z (2017) Differentiation of nestin‑negative human hair follicle outer root sheath cells into neurons in vitro. Mol Med Rep 16(1):95-100. doi: 10.3892/mmr.2017.6585 PMID: 28534946
Objective: To isolate nestin-negative outer root sheath cells (ORSCs) from adult healthy volunteers and investigate the neuronal differentiation of these cells.
Summary: The present study did not verify the value of neural differentiation into sphere-forming cells for therapeutic application, however, the differentiation of nestin-negative human hair follicle ORSCs into neurons in vitro may serve as a theoretical underpinning for neurodegenerative diseases and regenerative medicine.
Usage: IF (1:250)
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