Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ (2017) Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proc Natl Acad Sci U S A 114(18):E3709-E3718. doi: 10.1073/pnas.1619406114 PMID: 28420791
Objective: To identify adult enteric neural precursor cell (ENPC) that would enable a new understanding of the pathogenesis of enteric neuromuscular diseases as well as the development of novel regenerative therapies.
Summary: The results show significant turnover and neurogenesis of adult enteric neurons and provide a paradigm for understanding the enteric nervous system in health and disease.
Usage: IHC (1:400)
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