Go J, Kim JE, Kwak MH, Koh EK, Song SH, Sung JE, Kim DS, Hong JT, Hwang DY (2016) Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice. Nutr Neurosci 19(6):247-259. doi: 10.1179/1476830515Y.0000000025 PMID: 25923962
Objective: This study aimed to investigate the beneficial effects of Cheonggukjang (CGK) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on neurotoxic damages.
Summary: The short- and long-term memory loss induced by trimethyltin (TMT) treatment was significantly improved in the CGK-pretreated group in a dose-dependent manner. A dose-dependent increase in nerve growth factor (NGF) concentration, activation of the NGF receptor signaling pathway including the TrkA high affinity receptor and p75 NTR low affinity receptor was measured in all TMT/CGK-treated groups.
Usage: Western Blot
Related Products: NGFR (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)