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Thyroid hormone in the pathogenesis of congenital intestinal dysganglionosis

Wang F, Jing P, Zhan P, Zhang H (2020) Thyroid hormone in the pathogenesis of congenital intestinal dysganglionosis. Pediatr Dev Pathol 23(4):285-295. doi: 10.1177/1093526620908984 PMID: 32212960

Objective: To investigate the role of thyroid hormone (TH) in the pathogenesis of intestinal dysganglionosis (ID).

Summary: 6-propyl-2-thiouracil (PTU) inhibited TH production, reduced the number of enteric neurons, impaired intestinal motility, and impeded ENCC mitosis in zebrafish, suggesting a possible role of CH in the pathogenesis of ID.

Usage: Immunostaining (1:60); AB-N01AP: NGFr (mu p75) Rabbit Polyclonal

Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

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