Copeland EN (2022) Characterizing SERCA function in the hippocampal and prefrontal cortex regions of the brain from C57 and D2 mdx mice. Brock University St. Catharines, Ontario, Canada Thesis. PMID: 0
Objective: To investigate the differences between two models of Duchenne muscular dystrophy (DMD): D2 mouse model with young mice showing cognitive deficits, and C57, the traditional mouse model.
Summary: Impaired sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) function in both C57 and D2 mdx brain – perhaps due to heightened oxidative/nitrosative stress.
Usage: Western blot; NO-L-Cysteine Mouse Monoclonal, Conjugated as a marker of oxidative/nitrosative stress.
Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)