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Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts

Anderberg C, Li H, Fredriksson L, Andrae J, Betsholtz C, Li X, Eriksson U, Pietras K (2009) Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res 69(1):369-378. doi: 10.1158/0008-5472.CAN-08-2724 PMID: 19118022

Usage: Receptor stimulation and immunoprecipitation.  B16/mock, B16/PDGF-C, and porcine aortic endothelial cells stably expressing PDGFR-a (a-PAE) were stimulated with 100 ng/mL core PDGF-CC for 1 h on ice. Immunoprecipitation was done with an antibody to fibroblast growth factor-2.  Western blot analysis was done with 1 ug/mL antibody.

Related Products: Fibroblast Growth Factor Rabbit Polyclonal, mammalian (Cat. #AB-07)

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