The amygdala modulates the consolidation of memories of emotionally arousing experiences

McGaugh JL (2004) The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu Rev Neurosci 27:1-28. doi: 10.1146/annurev.neuro.27.070203.144157

Objective: This review focuses primarily on the findings of research investigating the role of the amygdala in modulating the consolidation of long-term memories.

Summary: The activation of neuromodulatory systems affecting the BLA and its projections to other brain regions involved in processing different kinds of information plays a key role in enabling emotionally significant experiences to be well remembered.

Usage: Selective lesions of cortical NB corticopetal cholinergic projections induced by 192-IgG saporin blocked the dose-dependent enhancement of inhibitory avoidance induced by posttraining intra-BLA infusions of NE.

Related Products: 192-IgG-SAP (Cat. #IT-01)

See Also:

• Power AE et al. Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala. PNAS 99(4):2315-2319, 2002.