Maddux JM, Kerfoot EC, Chatterjee S, Holland PC (2007) Dissociation of attention in learning and action: effects of lesions of the amygdala central nucleus, medial prefrontal cortex, and posterior parietal cortex. Behav Neurosci 121(1):63-79. doi: 10.1037/0735-7044.121.1.63
Objective: To study the effect of the amygdala central nucleus (CEA) on aspects of attention.
Summary: Lesions of the cholinergic afferents of the medial prefrontal cortex interfered with five-choice serial reaction time (5CSRT) performance but not with surprise-induced enhancement of learning, whereas lesions of cholinergic afferents of posterior parietal cortex impaired the latter effects but did not affect 5CSRT performance. CEA lesions impaired performance in both tasks.
Usage: Rats received bilateral infusions of 192IgG-saporin (0.25 μg/μl) into the posterior parietal cortex.
Related Products: 192-IgG-SAP (Cat. #IT-01)