Wiley RG (2001) Toxin-induced death of neurotrophin-sensitive neurons. (eds. Rush RA). In: Neurotrophin Protocols. Methods in Molecular Biology. 169:217-222. Humana Press. doi: 10.1385/1-59259-060-8:217
Summary: Wiley discusses some of the specifics of using 192-Saporin (Cat. #IT-01) to eliminate cells expressing the rat p75 low-affinity nerve growth factor receptor. Wiley also describes the sequence of events following treatment with 192-Saporin from binding of the immunotoxin through ribosomal inactivation and cell death. Methods of handling the immunotoxin and injection are also addressed.
Related Products: 192-IgG-SAP (Cat. #IT-01)