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  4. Enteric neurodegeneration is mediated through independent neuritic and somal mechanisms in rotenone and MPP+ toxicity.

Enteric neurodegeneration is mediated through independent neuritic and somal mechanisms in rotenone and MPP+ toxicity.

Virga DM, Capps J, Vohra BPS (2018) Enteric neurodegeneration is mediated through independent neuritic and somal mechanisms in rotenone and MPP+ toxicity. Neurochem Res 43(12):2288-2303. doi: 10.1007/s11064-018-2649-x

Objective: To investigate the mechanism by which enteric nervous system degeneration occurs in Parkinson’s Disease.

Summary: Therapies targeting both axonal and somal protection can be important in finding interventions for enteric symptoms in PD.

Usage: P75NTR antibody utilized (1:1000) to immunoselect enteric neural crest from the rest of the cells in the gut including stomach, small and large bowl and colon) from E12.5 Sprague CD1 mice.

Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)