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  4. Exposure to low environmental concentrations of manganese, lead, and cadmium alters the serotonin system of blue mussels.

Exposure to low environmental concentrations of manganese, lead, and cadmium alters the serotonin system of blue mussels.

Fraser M, Fortier M, Foucher D, Roumier P, Brousseau P, Fournier M, Surette C, Vaillancourt C (2018) Exposure to low environmental concentrations of manganese, lead, and cadmium alters the serotonin system of blue mussels. Environ Toxicol Chem 37:192-200. doi: 10.1002/etc.3942

Objective: To determine the effects of exposure to Mn, Pb, or Cd on serotonin levels, monoamine oxidase (MAO) activity, and serotonin transporter (SERT) levels in the blue mussel Mytilus edulis.

Summary: The results clearly indicate that low environmental concentrations of Mn, Pb, and Cd affect the serotonin system in blue mussels.

Usage: Membrane was exposed to anti-SERT primary antibody diluted 1:1000 in 5% PBS skimmed milk for 1.5 h at room temperature, then rinsed twice in deionized water, washed 3 times for 5 min in PBS, and rinsed 4 times in deionized water.

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