Wang B, Miao Y, Zhao Z, Zhong Y (2015) Inflammatory macrophages promotes development of diabetic encephalopathy. Cell Physiol Biochem 36:1142-1150. doi: 10.1159/000430285
Summary: Diabetes can cause neuroinflammation leading to dementia. Diabetes was induced in mice by injection of streptozotocin (STZ). In order to investigate the role of inflammatory macrophages in the development of diabetic encephalopathy, the authors used twice weekly 20-μg IP injections of Mac-1-SAP (Cat. #IT-06). Mice receiving Mac-1-SAP had significantly reduced numbers of inflammatory macrophages in the brain, and also reduced responses to STZ injection.
Related Products: Mac-1-SAP mouse/human (Cat. #IT-06)