Murray RC, Gilbert YE, Logan AS, Hebbard JC, Horner KA (2014) Striatal patch compartment lesions alter methamphetamine-induced behavior and immediate early gene expression in the striatum, substantia nigra and frontal cortex. Brain Struct Funct 219:1213-1229. doi: 10.1007/s00429-013-0559-x
Summary: In this work, the authors investigated the function of the patch compartment in abnormally repetitive motor actions (stereotypy) in response to a psychostimulant such as methampheta-mine (meth). Rats received bilateral injections of Dermorphin-SAP (Cat. #IT-12; 17 ng) into the rostral striatum. When treated with meth, lesioned animals displayed reduced stereotypy, increased motor activity, and enhanced c-Fos expression.
Related Products: Dermorphin-SAP / MOR-SAP (Cat. #IT-12)