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  4. Vestibular stimulation enhances hippocampal long-term potentiation via activation of cholinergic septohippocampal cells.

Vestibular stimulation enhances hippocampal long-term potentiation via activation of cholinergic septohippocampal cells.

Tai SK, Leung LS (2012) Vestibular stimulation enhances hippocampal long-term potentiation via activation of cholinergic septohippocampal cells. Behav Brain Res 232(1):174-182. doi: 10.1016/j.bbr.2012.04.013

Summary: It is known that vestibular stimulation induces acetylcholine release in the hippocampus. The authors hypothesized that this stimulation enhances long-term potentiation (LTP) in CA1 and depends on the activation of septohippocampal cholinergic neurons. Rats received 105-ng bilateral infusions of 192-IgG-SAP (Cat. #IT-01) into the medial septum. The data suggest that LTP enhancement during vestibular stimulation is mediated by cholinergic septohippocampal cells.

Related Products: 192-IgG-SAP (Cat. #IT-01)

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