Nag N, Baxter MG, Berger-Sweeney JE (2009) Efficacy of a murine-p75-saporin immunotoxin for selective lesions of basal forebrain cholinergic neurons in mice. Neurosci Lett 452:247-251. doi: 10.1016/j.neulet.2009.01.006
Summary: The authors tested a new version of mu p75-SAP (Cat. #IT-16) in mice. Mice received bilateral injections of 0.65 or 1.3 µg of immunotoxin into each lateral ventricle. Both amounts produced a complete loss of cholinergic neurons in the medial septum, while a dose-dependent loss of cholinergic neurons was seen in the nucleus basalis magnocellularis.
Related Products: mu p75-SAP (Cat. #IT-16)