- Streptavidin-ZAP (streptavidinylated saporin) combines with your biotinylated material to make a targeted toxin.
- Unlike a secondary antibody binding to a primary antibody, the bond between streptavidin and biotin is rapid, essentially non-reversible, unaffected by most extremes of pH, organic solvents and denaturing reagents. It is essentially the strongest known noncovalent biological bond between protein and ligand.
- Streptavidin-ZAP is super modular and works with biotinylated antibodies, peptides, growth factor, aptamers, anything that will recognize a cell surface receptor and can be biotinylated.
- We have kits available which will also include an appropriate control conjugate depending on the species of antibody you’re using or if you’re using a peptide.
- There are dozens of publications of using Streptavidin-ZAP in vivo.
- Streptavidin-ZAP is a useful research tool:
- screen your targeting agent
- confirm specificity
- move to the next stage and into animals
Note: discount code is expired